Which clinical sign is typically observed with a cervical mucous plug?

The presence of a cervical mucous plug is typically associated with the thickening of cervical mucus. This thickened mucus serves as a protective barrier, sealing the cervical canal during pregnancy to help prevent bacteria and other pathogens from ascending into the uterus. As the body prepares for labor, hormonal changes may cause this mucus plug to be expelled, often referred to as "losing the mucus plug." The thickening of cervical mucus is a physiological response designed to ensure the safety of the developing fetus during pregnancy.

In contrast, increased libido, irregular contractions, and lower back pain do not directly indicate the presence of a cervical mucous plug and are associated with various other aspects or stages of pregnancy.